Białystok – Łuków 168km (DK19, DK2, DW806, DK63)
Bydgoszcz – Łuków 422km (DK10, A1, A2, DK7, DK2 ,A2, DK2, DK63)
Gdańsk – Łuków 426km (S7, DW544, DW516, DK60, DW618, DK62, DW696, DK63)
Katowice – Łuków 373km (S86, S94, DW783, S7, S12, DW824, S48, DW809, DW808)
Kielce – Łuków 214km (S73, S7, S12, DW824, S48, DW809, DW808)
Kraków – Łuków 329km (S7, S12, DW824, S48, DW809, DW808)
Łódź – Łuków 258km (A1/E75, A2, DK7, S2, DK7, DK2, A2, DK2, DK63)
Olsztyn – Łuków 301km (S7, DW544, DW615, DK60, DW618, DK61, DW618, DK62, DW696, DK63)
Opole – Łuków 454km (DK45, DK11, DW487, DW382, DK74, S8, A1, A2, DK7, S8, S2, DK7, DK2, A2, DK2, DK63)
Poznań – Łuków 429km (A2, DK7, DK2 ,A2, DK2, DK63)
Rzeszów – Łuków 252km (DW878, DK97, S19, DW874, S17, DW874, DW809, DW808, DK63)
Szczecin – Łuków 684km (DW115, DK10, S3, A2, DK7, S2, DK7, DK2, A2, DK2, DK2, DK63)
Warszawa – Łuków 120km (DK2, A2 ,DK2, DK63)
Wrocław – Łuków 466km (DK98,DW368, S8, A1, A2, S2, DK7, DK2, A2, DK2, DK63)
Zielona Góra – Łuków 573km (DK32, S3, A2, DK7, DK2, A2, DK2, DK63)